Tagged: TCR

• T Cell Development

  A comprehensive guide to T lymphocyte development in the thymus, including stages of maturation, TCR rearrangement, positive and negative selection, and lineage commitment.

• Immune Repertoire

  A comprehensive guide to the complete collection of T cell and B cell receptors in an individual, including diversity metrics, clonality analysis, and clinical applications.

• V(D)J Recombination

  A comprehensive guide to the molecular mechanism that generates immune receptor diversity through somatic recombination of variable, diversity, and joining gene segments.

• T Cell Receptor Structure

  A comprehensive guide to the molecular architecture of the T cell receptor, including alpha and beta chains, complementarity-determining regions, and the mechanisms of antigen recognition.