Our Team

IMBER BIO was founded by physician-scientists at Washington University School of Medicine who are pioneering new approaches to autoimmune disease diagnosis through paired immune receptor sequencing.

Founding Team

Our founders bring together expertise in computational immunology, clinical pathology, translational research, and rheumatology.

Nicholas Borcherding
Co-Founder

Nicholas Borcherding

MD, PhD

Washington University School of Medicine

Nick is a physician-scientist whose work bridges computational immunology, clinical pathology, and transplant immunogenetics. As an Assistant Professor in the Department of Pathology and Immunology at Washington University, his clinical practice focuses on HLA testing for transplantation, autoimmunity, and cancer immunotherapy. His research explores how the adaptive immune system encodes and recalls disease experiences, integrating single-cell sequencing, systems immunology, and machine learning. He develops widely-used open-source software for immune repertoire and single-cell analysis, including scRepertoire.

Computational Immunology HLA & Transplant Immunogenetics Single-Cell Genomics
Philip Mudd
Co-Founder

Philip Mudd

MD, PhD

Washington University School of Medicine

Philip is an Assistant Professor of Emergency Medicine at Washington University, with a broad background in T cell immunology and viral infections. His laboratory focuses on human patients with viral respiratory diseases, performing translational immunology research using unique clinical specimens including human lymph node aspirations and lower airway samples. During the COVID-19 pandemic, he established a university-wide biospecimen repository that has supported over 14 publications. His work on COVID-19 and influenza immune responses has been published in Cell, Science, and Nature Immunology.

T Cell Immunology Viral Respiratory Diseases Translational Research
Michael Paley
Co-Founder

Michael Paley

MD, PhD

Washington University School of Medicine

Michael is an Assistant Professor in the Division of Rheumatology and Department of Pathology and Immunology at Washington University. He received his MD and PhD in Immunology from the University of Pennsylvania and directs the Ocular Rheumatology Clinic at Washington University. A Scholar in the Bursky Center for Human Immunology and Immunotherapy, he has received the Jane Bruckel Early Career Investigator Award in Axial Spondyloarthritis and ASCI's Young Physician-Scientist Award. His research focuses on HLA-B*27 and its role in acute anterior uveitis and axial spondyloarthritis, with the goal of identifying disease-causing cells to develop new diagnostics and therapeutics.

HLA-B27 Diseases Rheumatology Ocular Immunology

Interested in Collaboration?

We're always looking for research collaborators, clinical partners, and investors who share our vision of transforming immunodiagnostics.