Tagged: BCR

  • Immunoglobulin Gene Recombination

    A comprehensive guide to how B cells assemble unique antibody genes through V(D)J recombination at the immunoglobulin heavy and light chain loci.

  • B Cell Development

    A comprehensive guide to B lymphocyte development, from hematopoietic stem cells in the bone marrow through mature B cell subsets in the periphery.

  • Immune Repertoire

    A comprehensive guide to the complete collection of T cell and B cell receptors in an individual, including diversity metrics, clonality analysis, and clinical applications.

  • V(D)J Recombination

    A comprehensive guide to the molecular mechanism that generates immune receptor diversity through somatic recombination of variable, diversity, and joining gene segments.