scRepertoire is a comprehensive R toolkit for integrating TCR/BCR V(D)J sequencing with single-cell transcriptomic data. It provides a full suite of tools for clonotype assignment, diversity analysis, visualization, lineage tracking, and functional interpretation in coordination with Seurat or SingleCellExperiment.
Key Features
- Complete clonotype processing for TCR and BCR
- Rich visualizations for clonal expansion, V/J usage, diversity, and lineage
- Seamless integration with Seurat workflows
- Compatible with ImmApex, ImmLynx, Ibex/Trex, and Moose
- Designed for reproducible single-cell immunology analysis