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Ibex

Co-embedding BCR amino acid sequences and RNA Expression.

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Installation

R: devtools::install_github("BorchLab/Ibex")

Ibex is a deep-learning framework for generating low-dimensional embeddings from BCR immune receptor sequences. Built with Keras and trained on either amino-acid physicochemical properties or raw sequence tokens, Ibex provides a flexible convolutional neural network architecture tailored for BCR single-chain modeling.

Key Features

  • Convolutional neural networks optimized for receptor sequence analysis
  • Embeddings derived from amino-acid properties or direct sequence inputs